Infecţia cu E.coli – simptome, cauze, tratament

Tratament in infectia urinara cu e coli

It took two months and three courses of different antibiotics before Paolo's infection was successfully treated.

Episodul 33 - Infecțiile Urinare în Sarcină - ITU - Cistită- Pielonefrită - - SondaJJ - PROM

Nobody knows where he picked up the infection. Paolo is a 55 year old University Professor in Rome, Italy.

Empirical antibiotic treatment could solve a part of the uncomplicated infections, but it is necessary to also consider its negative effects, such as increasing the antimicrobial resistance and the number of recurrent infections.

In August ofPaolo had gone motor-boating alone to Ponza, a small island off the coast of Italy. After arrival in Ponza, he felt that he had symptoms of a urinary tract infection, but did not pay cancer de prostata pdf 2021 much attention at the time, because he thought his symptoms could have been due to dehydration from the summer heat.

After a while, however, he developed a fever with shaking chills and the symptoms of his urinary tract infection intensified.

tratament in infectia urinara cu e coli

He consulted with his brother-in-law, who is a medical doctor and was spending his holidays in Ponza. His brother-in-law suggested that he take ciprofloxacin, a fluoroquinolone antibiotic which is one of the most frequently used antibiotics for urinary tract infections.

Sus - Tratament medicamentos - Odata ce medicul a diagnosticat infectia de tract urinar, in urma uroculturii si a antibiogramei, va prescrie tratament cu antibiotice. In functie de gravitatea infectiei, tratamentul poate dura intre 3 si 14 zile. Tratamentul standard presupune utilizarea de trei zile a unei combinatii de medicamente: trimetroprim si sulfametoxazol. Bolnavilor alergici la sulfamide le sunt prescrise doar trimetroprim. Chiar daca simptomele de infectie dispar dupa una-doua zile, este recomandat ca tratamentul sa se faca integral.

Ciprofloxacin can be given by mouth, so is easy to take and is usually effective in treating urinary tract infections. His condition did not improve over the next three days and his fever did not abate. Despite this, he continued the course of ciprofloxacin for a week or more, with the hope of being well enough to motor-boat back to Rome and seek a full medical examination and laboratory tests.

tratament in infectia urinara cu e coli

Paolo was on the island of Ponza where there was no possibility of laboratory testing of his urine to better understand which antibiotics the bug could be treated with. He was aware that it would be important to know the results of his urine culture in order for a doctor to prescribe the correct antibiotic. Since he was afraid to motor-boat back to Rome by himself in case he became very ill, his brother-in-law accompanied him.

Infecțiile urinare complicate

On arrival at the mainland, he immediately went to a large hospital in Rome where he had a urine culture and clinical examination, which confirmed he had a complicated urinary tract infection. He was also found to have an enlarged prostate gland, which was the likely cause of his infection.

tratament in infectia urinara cu e coli

The culture showed that he was infected with a bacterium called Escherichia coli E. Paolo could not take trimethoprim-sulfamethoxazole, which is an oral antibacterial agent, because he was allergic to it.

Carbapenems can only be given intravenously, meaning spending some time at the hospital.

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His condition improved, but four days after his treatment was discontinued, he began having fever again and his symptoms of a urinary tract infection returned. He then called a friend of his, an infectious disease specialist, who suggested that he take fosfomycin by mouth in the correct dose for his infection.

He took this for 21 days.

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His symptoms resolved after that and he has been well ever since. Commentary: case notes While on holiday, Paolo developed a complicated urinary tract infection with an E. ESBLs are enzymes that make bacteria, most commonly E. Important points to note in this case are that Paolo had developed an infection with a community-acquired highly resistant E.

Notably, tratament in infectia urinara cu e coli.

Tratamentul infecțiilor urinare

The carbapenems, to which his E. Aside from the carbapenems, which are given intravenously and require some type of hospital stay, there were only few antibiotics that he could take that would be effective against his infection, and few that he could take by mouth. Additionally, he was allergic to one of them, trimethoprim-sulfamethoxazole.

The antibiotic that Paolo ended up taking was amoxicillin-clavulanic acid, which he took by mouth.

tratament in infectia urinara cu e coli

This antibiotic can appear sensitive in the laboratory, but is actually not effective against ESBL E. This is why his condition apparently improved during amoxicillin-clavulanic acid treatment, but the infection was not eradicated and suddenly relapsed after the therapeutic course. It is concerning that such highly resistant bacteria are spreading in the community and causing infections in patients with no contact with the hospital. Globally, ESBL- producing bacteria are being found as the cause of community-acquired infections, and tratament in infectia urinara cu e coli frequently urinary tract infections.

tratament in infectia urinara cu e coli

It is important to treat with the right antibiotic, since these types of highly resistant bacteria can cause patients to be sicker and to have a worse outcome. An important message for patients is that the right antibiotic needs to be prescribed for treatment.

tratament in infectia urinara cu e coli

It is therefore necessary to see a doctor and to have microbiological testing performed.